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Archaeal DnaG contains a conserved N-terminal RNA-binding domain and enables tailing of rRNA by the exosome
The archaeal exosome is a phosphorolytic 3′–5′ exoribonuclease complex. In a reverse reaction it synthesizes A-rich RNA tails. Its RNA-binding cap comprises the eukaryotic orthologs Rrp4 and Csl4, and an archaea-specific subunit annotated as DnaG. In Sulfolobus solfataricus DnaG and Rrp4 but not Csl...
Autores principales: | Hou, Linlin, Klug, Gabriele, Evguenieva-Hackenberg, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227792/ https://www.ncbi.nlm.nih.gov/pubmed/25326320 http://dx.doi.org/10.1093/nar/gku969 |
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