N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity

Heterochromatin protein 1 (HP1) is an evolutionarily conserved chromosomal protein that binds to lysine 9-methylated histone H3 (H3K9me), a hallmark of heterochromatin. Although HP1 phosphorylation has been described in several organisms, the biological implications of this modification remain large...

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Detalles Bibliográficos
Autores principales: Nishibuchi, Gohei, Machida, Shinichi, Osakabe, Akihisa, Murakoshi, Hiromu, Hiragami-Hamada, Kyoko, Nakagawa, Reiko, Fischle, Wolfgang, Nishimura, Yoshifumi, Kurumizaka, Hitoshi, Tagami, Hideaki, Nakayama, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227797/
https://www.ncbi.nlm.nih.gov/pubmed/25332400
http://dx.doi.org/10.1093/nar/gku995

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