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Uncovering pH-Dependent Transient States of Proteins with Buried Ionizable Residues
[Image: see text] The role of pH in regulating biological activity is ubiquitous, and understanding pH-mediated activity has traditionally relied on analyzing static biomolecular structures of highly populated ground states solved near physiological pH. However, recent advances have shown the increa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227812/ https://www.ncbi.nlm.nih.gov/pubmed/24842060 http://dx.doi.org/10.1021/ja5012564 |