Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays

[Image: see text] Identifying small molecules that selectively bind to structured RNA motifs remains an important challenge in developing potent and specific therapeutics. Most strategies to find RNA-binding molecules have identified highly charged compounds or aminoglycosides that commonly have mod...

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Detalles Bibliográficos
Autores principales: Sztuba-Solinska, Joanna, Shenoy, Shilpa R., Gareiss, Peter, Krumpe, Lauren R. H., Le Grice, Stuart F. J., O’Keefe, Barry R., Schneekloth, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227816/
https://www.ncbi.nlm.nih.gov/pubmed/24820959
http://dx.doi.org/10.1021/ja502754f

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