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Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells
BACKGROUND: Resistance to apoptosis induced by anti-cancer drugs is a major obstacle for the treatment of aggressive forms of breast cancer. Galectin-7 (gal-7) was recently shown to be specifically expressed in basal-like but not in luminal subtypes of human breast cancer. METHODS: We generated a mu...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228062/ https://www.ncbi.nlm.nih.gov/pubmed/25367122 http://dx.doi.org/10.1186/1471-2407-14-801 |