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The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma
BACKGROUND: Inhaled allergen challenge is a standard method to study airway responses to inflammatory provocation and evaluate the therapeutic potential of novel anti-inflammatory compounds in asthma. MEM 1414 is a novel oral PDE4 inhibitor with high affinity and selectivity creating the potential f...
Autores principales: | Leaker, Brian R, Singh, Dave, Ali, Ferhana Y, Barnes, Peter J, O’Connor, Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228152/ https://www.ncbi.nlm.nih.gov/pubmed/25351474 http://dx.doi.org/10.1186/1471-2466-14-166 |
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