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The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma

BACKGROUND: Inhaled allergen challenge is a standard method to study airway responses to inflammatory provocation and evaluate the therapeutic potential of novel anti-inflammatory compounds in asthma. MEM 1414 is a novel oral PDE4 inhibitor with high affinity and selectivity creating the potential f...

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Detalles Bibliográficos
Autores principales: Leaker, Brian R, Singh, Dave, Ali, Ferhana Y, Barnes, Peter J, O’Connor, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228152/
https://www.ncbi.nlm.nih.gov/pubmed/25351474
http://dx.doi.org/10.1186/1471-2466-14-166

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