Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers

Recent observations connected DNA cytosine deaminase APOBEC3B to the genetic evolution of breast cancer. We addressed whether APOBEC3B is associated with breast cancer clinical outcomes. APOBEC3B messenger RNA (mRNA) levels were related in 1,491 primary breast cancers to disease-free (DFS), metastas...

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Detalles Bibliográficos
Autores principales: Sieuwerts, Anieta M., Willis, Scooter, Burns, Michael B., Look, Maxime P., Gelder, Marion E. Meijer-Van, Schlicker, Andreas, Heideman, Marinus R., Jacobs, Heinz, Wessels, Lodewyk, Leyland-Jones, Brian, Gray, Kathryn P., Foekens, John A., Harris, Reuben S., Martens, John W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228172/
https://www.ncbi.nlm.nih.gov/pubmed/25123150
http://dx.doi.org/10.1007/s12672-014-0196-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228172/
https://www.ncbi.nlm.nih.gov/pubmed/25123150
http://dx.doi.org/10.1007/s12672-014-0196-8

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