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Characterisation of CD154(+) T cells following ex vivo allergen stimulation illustrates distinct T cell responses to seasonal and perennial allergens in allergic and non-allergic individuals

BACKGROUND: Allergic sensitisation has been ascribed to a dysregulated relationship between allergen-specific Th1, Th2 and regulatory T cells. We sought to utilise our short-term CD154 detection method to further analyse the relationship between these T cell subsets and investigate differences betwe...

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Detalles Bibliográficos
Autores principales: Smith, Karen A, Gray, Nicola J, Saleh, Femi, Cheek, Elizabeth, Frew, Anthony J, Kern, Florian, Tarzi, Michael D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228241/
https://www.ncbi.nlm.nih.gov/pubmed/24188324
http://dx.doi.org/10.1186/1471-2172-14-49