Cargando…
Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature
A lymphoepithelioma-like carcinoma (LLC), characterized by a carcinoma with stromal heavy lymphocyte infiltration, is one of the histological patterns observed in patients with Epstein-Barr virus (EBV)-associated gastric carcinoma. Although this entity is hard to be recognized in the biopsy specimen...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228252/ https://www.ncbi.nlm.nih.gov/pubmed/24188515 http://dx.doi.org/10.1186/1746-1596-8-184 |
_version_ | 1782343943975862272 |
---|---|
author | Bittar, Zeid Fend, Falko Quintanilla-Martinez, Leticia |
author_facet | Bittar, Zeid Fend, Falko Quintanilla-Martinez, Leticia |
author_sort | Bittar, Zeid |
collection | PubMed |
description | A lymphoepithelioma-like carcinoma (LLC), characterized by a carcinoma with stromal heavy lymphocyte infiltration, is one of the histological patterns observed in patients with Epstein-Barr virus (EBV)-associated gastric carcinoma. Although this entity is hard to be recognized in the biopsy specimens, pathologists and clinicians should acknowledge this subset of gastric cancer because it generally has a better prognosis than other forms of EBV-associated gastric carcinomas and conventional gastric carcinomas. This might be due to the fact that the patient's inflammatory response may prevent the spread of tumor through the gastric wall and to the lymph nodes or remote organs. We report a case of EBV-positive, microsatellite stable LLC as a rare morphologic variant of gastric carcinoma. VIRTUAL SLIDES: The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1360498724104351. |
format | Online Article Text |
id | pubmed-4228252 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42282522014-11-13 Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature Bittar, Zeid Fend, Falko Quintanilla-Martinez, Leticia Diagn Pathol Case Report A lymphoepithelioma-like carcinoma (LLC), characterized by a carcinoma with stromal heavy lymphocyte infiltration, is one of the histological patterns observed in patients with Epstein-Barr virus (EBV)-associated gastric carcinoma. Although this entity is hard to be recognized in the biopsy specimens, pathologists and clinicians should acknowledge this subset of gastric cancer because it generally has a better prognosis than other forms of EBV-associated gastric carcinomas and conventional gastric carcinomas. This might be due to the fact that the patient's inflammatory response may prevent the spread of tumor through the gastric wall and to the lymph nodes or remote organs. We report a case of EBV-positive, microsatellite stable LLC as a rare morphologic variant of gastric carcinoma. VIRTUAL SLIDES: The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1360498724104351. BioMed Central 2013-11-04 /pmc/articles/PMC4228252/ /pubmed/24188515 http://dx.doi.org/10.1186/1746-1596-8-184 Text en Copyright © 2013 Bittar et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Bittar, Zeid Fend, Falko Quintanilla-Martinez, Leticia Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature |
title | Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature |
title_full | Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature |
title_fullStr | Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature |
title_full_unstemmed | Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature |
title_short | Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature |
title_sort | lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228252/ https://www.ncbi.nlm.nih.gov/pubmed/24188515 http://dx.doi.org/10.1186/1746-1596-8-184 |
work_keys_str_mv | AT bittarzeid lymphoepitheliomalikecarcinomaofthestomachacasereportandreviewoftheliterature AT fendfalko lymphoepitheliomalikecarcinomaofthestomachacasereportandreviewoftheliterature AT quintanillamartinezleticia lymphoepitheliomalikecarcinomaofthestomachacasereportandreviewoftheliterature |