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Genomic amplification of MYC as double minutes in a patient with APL-like leukemia

BACKGROUND: Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML) characterized by a PML-RARA fusion due to a translocation t(15;17). Its sensitivity to treatment with all-trans retinoic acid (ATRA), which causes differentiation of the abnormal promyelocytes, combined with...

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Detalles Bibliográficos
Autores principales:	Poddighe, Pino J, Wessels, Hans, Merle, Pauline, Westers, Marisa, Bhola, Shama, Loonen, Anne, Zweegman, Sonja, Ossenkoppele, Gert J, Wondergem, Marielle J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228273/ https://www.ncbi.nlm.nih.gov/pubmed/25392715 http://dx.doi.org/10.1186/s13039-014-0067-6

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