Cucurbitacin I blocks cerebrospinal fluid and platelet derived growth factor-BB stimulation of leptomeningeal and meningioma DNA synthesis

BACKGROUND: Currently, there are no consistently effective chemotherapies for recurrent and inoperable meningiomas. Recently, cucurbitacin I (JSI-124), a naturally occurring tetracyclic triterpenoid compound used as folk medicines has been found to have cytoxic and anti-proliferative properties in s...

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Detalles Bibliográficos
Autores principales: Johnson, Mahlon D, O’Connell, Mary J, Walter, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228312/
https://www.ncbi.nlm.nih.gov/pubmed/24188277
http://dx.doi.org/10.1186/1472-6882-13-303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228312/
https://www.ncbi.nlm.nih.gov/pubmed/24188277
http://dx.doi.org/10.1186/1472-6882-13-303

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