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Cucurbitacin I blocks cerebrospinal fluid and platelet derived growth factor-BB stimulation of leptomeningeal and meningioma DNA synthesis

BACKGROUND: Currently, there are no consistently effective chemotherapies for recurrent and inoperable meningiomas. Recently, cucurbitacin I (JSI-124), a naturally occurring tetracyclic triterpenoid compound used as folk medicines has been found to have cytoxic and anti-proliferative properties in s...

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Detalles Bibliográficos
Autores principales:	Johnson, Mahlon D, O’Connell, Mary J, Walter, Kevin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228312/ https://www.ncbi.nlm.nih.gov/pubmed/24188277 http://dx.doi.org/10.1186/1472-6882-13-303

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