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Hybridization approach to in-line and off-axis (electron) holography for superior resolution and phase sensitivity
Holography - originally developed for correcting spherical aberration in transmission electron microscopes - is now used in a wide range of disciplines that involve the propagation of waves, including light optics, electron microscopy, acoustics and seismology. In electron microscopy, the two primar...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228327/ https://www.ncbi.nlm.nih.gov/pubmed/25387480 http://dx.doi.org/10.1038/srep07020 |
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author | Ozsoy-Keskinbora, C. Boothroyd, C. B. Dunin-Borkowski, R. E. van Aken, P. A. Koch, C. T. |
author_facet | Ozsoy-Keskinbora, C. Boothroyd, C. B. Dunin-Borkowski, R. E. van Aken, P. A. Koch, C. T. |
author_sort | Ozsoy-Keskinbora, C. |
collection | PubMed |
description | Holography - originally developed for correcting spherical aberration in transmission electron microscopes - is now used in a wide range of disciplines that involve the propagation of waves, including light optics, electron microscopy, acoustics and seismology. In electron microscopy, the two primary modes of holography are Gabor's original in-line setup and an off-axis approach that was developed subsequently. These two techniques are highly complementary, offering superior phase sensitivity at high and low spatial resolution, respectively. All previous investigations have focused on improving each method individually. Here, we show how the two approaches can be combined in a synergetic fashion to provide phase information with excellent sensitivity across all spatial frequencies, low noise and an efficient use of electron dose. The principle is also expected to be widely to applications of holography in light optics, X-ray optics, acoustics, ultra-sound, terahertz imaging, etc. |
format | Online Article Text |
id | pubmed-4228327 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-42283272014-11-13 Hybridization approach to in-line and off-axis (electron) holography for superior resolution and phase sensitivity Ozsoy-Keskinbora, C. Boothroyd, C. B. Dunin-Borkowski, R. E. van Aken, P. A. Koch, C. T. Sci Rep Article Holography - originally developed for correcting spherical aberration in transmission electron microscopes - is now used in a wide range of disciplines that involve the propagation of waves, including light optics, electron microscopy, acoustics and seismology. In electron microscopy, the two primary modes of holography are Gabor's original in-line setup and an off-axis approach that was developed subsequently. These two techniques are highly complementary, offering superior phase sensitivity at high and low spatial resolution, respectively. All previous investigations have focused on improving each method individually. Here, we show how the two approaches can be combined in a synergetic fashion to provide phase information with excellent sensitivity across all spatial frequencies, low noise and an efficient use of electron dose. The principle is also expected to be widely to applications of holography in light optics, X-ray optics, acoustics, ultra-sound, terahertz imaging, etc. Nature Publishing Group 2014-11-12 /pmc/articles/PMC4228327/ /pubmed/25387480 http://dx.doi.org/10.1038/srep07020 Text en Copyright © 2014, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ |
spellingShingle | Article Ozsoy-Keskinbora, C. Boothroyd, C. B. Dunin-Borkowski, R. E. van Aken, P. A. Koch, C. T. Hybridization approach to in-line and off-axis (electron) holography for superior resolution and phase sensitivity |
title | Hybridization approach to in-line and off-axis (electron) holography for superior resolution and phase sensitivity |
title_full | Hybridization approach to in-line and off-axis (electron) holography for superior resolution and phase sensitivity |
title_fullStr | Hybridization approach to in-line and off-axis (electron) holography for superior resolution and phase sensitivity |
title_full_unstemmed | Hybridization approach to in-line and off-axis (electron) holography for superior resolution and phase sensitivity |
title_short | Hybridization approach to in-line and off-axis (electron) holography for superior resolution and phase sensitivity |
title_sort | hybridization approach to in-line and off-axis (electron) holography for superior resolution and phase sensitivity |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228327/ https://www.ncbi.nlm.nih.gov/pubmed/25387480 http://dx.doi.org/10.1038/srep07020 |
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