Cargando…

Abnormal expression of paxillin correlates with tumor progression and poor survival in patients with gastric cancer

BACKGROUND: Paxillin (PXN) has been found to be aberrantly regulated in various malignancies and involved in tumor growth and invasion. The clinicopathological and prognostic significance of PXN in gastric cancer is still unclear. METHODS: The expression of PXN was determined in paired gastric cance...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Dong-liang, Wang, Zhi-qiang, Ren, Chao, Zeng, Zhao-lei, Wang, De-shen, Luo, Hui-yan, Wang, Feng, Qiu, Miao-zhen, Bai, Long, Zhang, Dong-sheng, Wang, Feng-hua, Li, Yu-hong, Xu, Rui-hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228400/ https://www.ncbi.nlm.nih.gov/pubmed/24180516 http://dx.doi.org/10.1186/1479-5876-11-277

Ejemplares similares

Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer
por: Chen, Dong-Liang, et al.
Publicado: (2013)

Adjuvant Chemotherapy for Elderly Patients with Gastric Cancer after D2 Gastrectomy
por: Jin, Ying, et al.
Publicado: (2013)

Prognostic effects of 25-hydroxyvitamin D levels in gastric cancer
por: Ren, Chao, et al.
Publicado: (2012)

S-1-Based Chemotherapy versus Capecitabine-Based Chemotherapy as First-Line Treatment for Advanced Gastric Carcinoma: A Meta-Analysis
por: He, Ming-ming, et al.
Publicado: (2013)

Prognostic value of preoperative serum lactate dehydrogenase levels for resectable gastric cancer and prognostic nomograms
por: Wang, Zi-Xian, et al.
Publicado: (2016)

Phase II clinical trial of S‐1 plus nanoparticle albumin‐bound paclitaxel in untreated patients with metastatic gastric cancer
por: He, Ming‐ming, et al.
Publicado: (2018)

Paxillin expression is closely linked to the pathogenesis, progression and prognosis of gastric carcinomas
por: XIAO, LI-JUN, et al.
Publicado: (2014)

The status of HBV infection influences metastatic pattern and survival in Chinese patients with pancreatic cancer
por: Wei, Xiao-li, et al.
Publicado: (2013)

Chemotherapy plus bevacizumab versus chemotherapy plus cetuximab as first-line treatment for patients with metastatic colorectal cancer: Results of a registry-based cohort analysis
por: Bai, Long, et al.
Publicado: (2016)

Clinicopathological characteristics and prognostic analysis of Lauren classification in gastric adenocarcinoma in China
por: Qiu, Miao-zhen, et al.
Publicado: (2013)

Paxillin functions as an oncogene in human gliomas by promoting cell migration and invasion
por: Chen, Bing, et al.
Publicado: (2016)

The Tumor-Log Odds of Positive Lymph Nodes-Metastasis Staging System, a Promising New Staging System for Gastric Cancer after D2 Resection in China
por: Qiu, Miao-zhen, et al.
Publicado: (2012)

Phase II trial of S-1 plus leucovorin in patients with advanced gastric cancer and clinical prediction by S-1 pharmacogenetic pathway
por: He, Ming-ming, et al.
Publicado: (2016)

A plasma cytokine and angiogenic factor (CAF) analysis for selection of bevacizumab therapy in patients with metastatic colorectal cancer
por: Bai, Long, et al.
Publicado: (2015)

DNA polymeraseη protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy
por: Teng, Kai-yuan, et al.
Publicado: (2010)

Detection of carcinoembryonic antigen messenger RNA in blood using quantitative real-time reverse transcriptase-polymerase chain reaction to predict recurrence of gastric adenocarcinoma
por: Qiu, Miao-zhen, et al.
Publicado: (2010)

Enah overexpression is correlated with poor survival and aggressive phenotype in gastric cancer
por: Chen, Di, et al.
Publicado: (2018)

Are Risk Factors Associated with Outcomes in Pancreatic Cancer?
por: Wang, De-shen, et al.
Publicado: (2012)

Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression
por: Chen, Dong-liang, et al.
Publicado: (2016)

The survival benefit of palliative gastrectomy and/or metastasectomy in gastric cancer patients with synchronous metastasis: a population-based study using propensity score matching and coarsened exact matching
por: Yang, Lu-Ping, et al.
Publicado: (2019)

Correction to: Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression
por: Chen, Dong-liang, et al.
Publicado: (2021)

Paxillin brings peace to microtubules
por: Leslie, Mitch
Publicado: (2014)

CDC20 overexpression predicts a poor prognosis for patients with colorectal cancer
por: Wu, Wen-jing, et al.
Publicado: (2013)

Copper-transporting P-type adenosine triphosphatase (ATP7A) is associated with platinum-resistance in non-small cell lung cancer (NSCLC)
por: Li, Zhuang-hua, et al.
Publicado: (2012)

SphK1‐driven autophagy potentiates focal adhesion paxillin‐mediated metastasis in colorectal cancer
por: Wu, Jiang‐Ni, et al.
Publicado: (2021)

A phase I study of toripalimab, an anti‐PD‐1 antibody, in patients with refractory malignant solid tumors
por: Wei, Xiao‐Li, et al.
Publicado: (2020)

Focal adhesion kinase and paxillin promote migration and adhesion to fibronectin by swine skeletal muscle satellite cells
por: Wang, Dan, et al.
Publicado: (2016)

FcγRIIA and IIIA polymorphisms predict clinical outcome of trastuzumab-treated metastatic gastric cancer
por: Wang, De-shen, et al.
Publicado: (2017)

Low preoperative albumin-globulin score predicts favorable survival in esophageal squamous cell carcinoma
por: Zhang, Fei, et al.
Publicado: (2016)

The Role of Non-Curative Surgery in Incurable, Asymptomatic Advanced Gastric Cancer
por: He, Ming-ming, et al.
Publicado: (2013)

Author Correction: Enah overexpression is correlated with poor survival and aggressive phenotype in gastric cancer
por: Chen, Di, et al.
Publicado: (2019)

Vinculin modulation of paxillin–FAK interactions regulates ERK to control survival and motility
por: Subauste, M. Cecilia, et al.
Publicado: (2004)

Primary small cell carcinoma of the esophagus: clinicopathological study of 44 cases
por: Chen, Wei-Wei, et al.
Publicado: (2014)

Right- and left-sided colorectal cancers respond differently to cetuximab
por: Wang, Feng, et al.
Publicado: (2015)

Development and Evaluation of Monoclonal Antibodies for Paxilline
por: Maragos, Chris M.
Publicado: (2015)

Comparison of survival between right‐sided and left‐sided colon cancer in different situations
por: Qiu, Miao‐Zhen, et al.
Publicado: (2018)

The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL)
por: West, Kip A., et al.
Publicado: (2001)

Patients with Old Age or Proximal Tumors Benefit from Metabolic Syndrome in Early Stage Gastric Cancer
por: Wei, Xiao-li, et al.
Publicado: (2014)

Proposal for a New TNM Stage based on the 7(th) and 8(th) American Joint Committee on Cancer pTNM Staging Classification for Gastric Cancer
por: Qiu, Miao-Zhen, et al.
Publicado: (2018)

FAK and paxillin dynamics at focal adhesions in the protrusions of migrating cells
por: Hu, Ying-Li, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_loi38e0g77cj8lorsitqf2bsvr