Radiosynovectomy of the elbow joint synovitis in rheumatoid arthritis treated with Lutetium - 177 labeled hydroxylapatite (Lu-177 HA) particulates; first case report and image of Lu -177 HA in the elbow joint

Rheumatoid arthritis is a chronic disease that is mainly characterized by asymmetric erosive synovitis, particularly affecting the peripheral joints. Radiation synovectomy or radiosynovectomy, also known as radiosynoviorthesis was first described in 1950's as a adjuvant treatment for rheumatoid...

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Autores principales: Kamaleshwaran, Koramadai Karuppusamy, Rajamani, Venkataraman, Thirumalaisamy, Subbiah Gounder, Chakraborty, Sudipta, Kalarikal, Radhakrishnan, Mohanan, Vyshakh, Shinto, Ajit Sugunan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228597/
https://www.ncbi.nlm.nih.gov/pubmed/25400373
http://dx.doi.org/10.4103/0972-3919.142644
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author Kamaleshwaran, Koramadai Karuppusamy
Rajamani, Venkataraman
Thirumalaisamy, Subbiah Gounder
Chakraborty, Sudipta
Kalarikal, Radhakrishnan
Mohanan, Vyshakh
Shinto, Ajit Sugunan
author_facet Kamaleshwaran, Koramadai Karuppusamy
Rajamani, Venkataraman
Thirumalaisamy, Subbiah Gounder
Chakraborty, Sudipta
Kalarikal, Radhakrishnan
Mohanan, Vyshakh
Shinto, Ajit Sugunan
author_sort Kamaleshwaran, Koramadai Karuppusamy
collection PubMed
description Rheumatoid arthritis is a chronic disease that is mainly characterized by asymmetric erosive synovitis, particularly affecting the peripheral joints. Radiation synovectomy or radiosynovectomy, also known as radiosynoviorthesis was first described in 1950's as a adjuvant treatment for rheumatoid arthritis. Radiosynovectomy is based on the irradiation of the joint synovium by the intra-articular administration of various β-emitting radiopharmaceuticals. Lu-177 has presence of gamma photons of imagable energy with low abundance which provides the additional benefit of carrying out simultaneous scintigraphy. We describe the first case report of use of Lu-177 hydroxylapatite particulates in a 35-year-old female patient who was presented with elbow joint synovitis due to rheumatoid arthritis.
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spelling pubmed-42285972014-11-14 Radiosynovectomy of the elbow joint synovitis in rheumatoid arthritis treated with Lutetium - 177 labeled hydroxylapatite (Lu-177 HA) particulates; first case report and image of Lu -177 HA in the elbow joint Kamaleshwaran, Koramadai Karuppusamy Rajamani, Venkataraman Thirumalaisamy, Subbiah Gounder Chakraborty, Sudipta Kalarikal, Radhakrishnan Mohanan, Vyshakh Shinto, Ajit Sugunan Indian J Nucl Med Case Report Rheumatoid arthritis is a chronic disease that is mainly characterized by asymmetric erosive synovitis, particularly affecting the peripheral joints. Radiation synovectomy or radiosynovectomy, also known as radiosynoviorthesis was first described in 1950's as a adjuvant treatment for rheumatoid arthritis. Radiosynovectomy is based on the irradiation of the joint synovium by the intra-articular administration of various β-emitting radiopharmaceuticals. Lu-177 has presence of gamma photons of imagable energy with low abundance which provides the additional benefit of carrying out simultaneous scintigraphy. We describe the first case report of use of Lu-177 hydroxylapatite particulates in a 35-year-old female patient who was presented with elbow joint synovitis due to rheumatoid arthritis. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4228597/ /pubmed/25400373 http://dx.doi.org/10.4103/0972-3919.142644 Text en Copyright: © Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kamaleshwaran, Koramadai Karuppusamy
Rajamani, Venkataraman
Thirumalaisamy, Subbiah Gounder
Chakraborty, Sudipta
Kalarikal, Radhakrishnan
Mohanan, Vyshakh
Shinto, Ajit Sugunan
Radiosynovectomy of the elbow joint synovitis in rheumatoid arthritis treated with Lutetium - 177 labeled hydroxylapatite (Lu-177 HA) particulates; first case report and image of Lu -177 HA in the elbow joint
title Radiosynovectomy of the elbow joint synovitis in rheumatoid arthritis treated with Lutetium - 177 labeled hydroxylapatite (Lu-177 HA) particulates; first case report and image of Lu -177 HA in the elbow joint
title_full Radiosynovectomy of the elbow joint synovitis in rheumatoid arthritis treated with Lutetium - 177 labeled hydroxylapatite (Lu-177 HA) particulates; first case report and image of Lu -177 HA in the elbow joint
title_fullStr Radiosynovectomy of the elbow joint synovitis in rheumatoid arthritis treated with Lutetium - 177 labeled hydroxylapatite (Lu-177 HA) particulates; first case report and image of Lu -177 HA in the elbow joint
title_full_unstemmed Radiosynovectomy of the elbow joint synovitis in rheumatoid arthritis treated with Lutetium - 177 labeled hydroxylapatite (Lu-177 HA) particulates; first case report and image of Lu -177 HA in the elbow joint
title_short Radiosynovectomy of the elbow joint synovitis in rheumatoid arthritis treated with Lutetium - 177 labeled hydroxylapatite (Lu-177 HA) particulates; first case report and image of Lu -177 HA in the elbow joint
title_sort radiosynovectomy of the elbow joint synovitis in rheumatoid arthritis treated with lutetium - 177 labeled hydroxylapatite (lu-177 ha) particulates; first case report and image of lu -177 ha in the elbow joint
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228597/
https://www.ncbi.nlm.nih.gov/pubmed/25400373
http://dx.doi.org/10.4103/0972-3919.142644
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