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Hutchinson – Gilford progeria syndrome: A rare case report

Hutchinson – Gilford Progeria Syndrome is a rare genetic disorder characterized by premature aging involving the skin, bones, heart, and blood vessels. We report a three-year-old boy with clinical manifestations characteristic of this syndrome. He had a characteristic “plucked-bird” appearance, prom...

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Detalles Bibliográficos
Autores principales: Kashyap, Subhash, Shanker, Vinay, Sharma, Neeraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228646/
https://www.ncbi.nlm.nih.gov/pubmed/25396134
http://dx.doi.org/10.4103/2229-5178.142507
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author Kashyap, Subhash
Shanker, Vinay
Sharma, Neeraj
author_facet Kashyap, Subhash
Shanker, Vinay
Sharma, Neeraj
author_sort Kashyap, Subhash
collection PubMed
description Hutchinson – Gilford Progeria Syndrome is a rare genetic disorder characterized by premature aging involving the skin, bones, heart, and blood vessels. We report a three-year-old boy with clinical manifestations characteristic of this syndrome. He had a characteristic “plucked-bird” appearance, prominent eyes and scalp veins, senile look, loss of scalp hair, eyebrows, and eyelashes, stunted growth, and mottled pigmentation with sclerodermatous changes over the trunk and lower limbs. Radiological changes and decreased high-density lipoprotein (HDL) levels were also characteristic of the syndrome. This interesting case is reported for its rarity.
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spelling pubmed-42286462014-11-13 Hutchinson – Gilford progeria syndrome: A rare case report Kashyap, Subhash Shanker, Vinay Sharma, Neeraj Indian Dermatol Online J Case Report Hutchinson – Gilford Progeria Syndrome is a rare genetic disorder characterized by premature aging involving the skin, bones, heart, and blood vessels. We report a three-year-old boy with clinical manifestations characteristic of this syndrome. He had a characteristic “plucked-bird” appearance, prominent eyes and scalp veins, senile look, loss of scalp hair, eyebrows, and eyelashes, stunted growth, and mottled pigmentation with sclerodermatous changes over the trunk and lower limbs. Radiological changes and decreased high-density lipoprotein (HDL) levels were also characteristic of the syndrome. This interesting case is reported for its rarity. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4228646/ /pubmed/25396134 http://dx.doi.org/10.4103/2229-5178.142507 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kashyap, Subhash
Shanker, Vinay
Sharma, Neeraj
Hutchinson – Gilford progeria syndrome: A rare case report
title Hutchinson – Gilford progeria syndrome: A rare case report
title_full Hutchinson – Gilford progeria syndrome: A rare case report
title_fullStr Hutchinson – Gilford progeria syndrome: A rare case report
title_full_unstemmed Hutchinson – Gilford progeria syndrome: A rare case report
title_short Hutchinson – Gilford progeria syndrome: A rare case report
title_sort hutchinson – gilford progeria syndrome: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228646/
https://www.ncbi.nlm.nih.gov/pubmed/25396134
http://dx.doi.org/10.4103/2229-5178.142507
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