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Extracellular Vesicles: A Platform for the Structure Determination of Membrane Proteins by Cryo-EM
Membrane protein-enriched extracellular vesicles (MPEEVs) provide a platform for studying intact membrane proteins natively anchored with the correct topology in genuine biological membranes. This approach circumvents the need to conduct tedious detergent screens for solubilization, purification, an...
Autores principales: | Zeev-Ben-Mordehai, Tzviya, Vasishtan, Daven, Siebert, C. Alistair, Whittle, Cathy, Grünewald, Kay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229021/ https://www.ncbi.nlm.nih.gov/pubmed/25438672 http://dx.doi.org/10.1016/j.str.2014.09.005 |
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