Cargando…

Potent Anti-Cancer Effect of 3′-Hydroxypterostilbene in Human Colon Xenograft Tumors

Here we report that 3′-hydroxypterostilbene (HPSB), a natural pterostilbene analogue, was more potent than pterostilbene against the growth of human cancer cells (COLO 205, HCT-116, and HT-29) with measured IC(50) values of 9.0, 40.2, and 70.9 µM, respectively. We found that HPSB effectively inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Tzu-Chun, Lai, Ching-Shu, Chung, Min-Ching, Kalyanam, Nagabhushanam, Majeed, Muhammed, Ho, Chi-Tang, Ho, Yuan-Soon, Pan, Min-Hsiung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229093/ https://www.ncbi.nlm.nih.gov/pubmed/25389774 http://dx.doi.org/10.1371/journal.pone.0111814

Ejemplares similares

Biological actions and molecular effects of resveratrol, pterostilbene, and 3′-hydroxypterostilbene
por: Tsai, Hui-Yun, et al.
Publicado: (2016)

Evaluation of 90 day repeated dose oral toxicity and reproductive/developmental toxicity of 3'-hydroxypterostilbene in experimental animals
por: Majeed, Muhammed, et al.
Publicado: (2017)

A Natural Degradant of Curcumin, Feruloylacetone Inhibits Cell Proliferation via Inducing Cell Cycle Arrest and a Mitochondrial Apoptotic Pathway in HCT116 Colon Cancer Cells
por: Chou, Yu-Ting, et al.
Publicado: (2021)

Efficacy and Safety of Tetrahydrocurcuminoids for the Treatment of Canker Sore and Gingivitis
por: Majeed, Muhammed, et al.
Publicado: (2020)

An Open-Label Pilot Study on Macumax Supplementation for Dry-Type Age-Related Macular Degeneration
por: Majeed, Muhammed, et al.
Publicado: (2021)

Calebin-A prevents HFD-induced obesity in mice by promoting thermogenesis and modulating gut microbiota
por: Lee, Pei-Sheng, et al.
Publicado: (2022)

A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study
por: Majeed, Muhammed, et al.
Publicado: (2023)

A pilot, randomized, double‐blind, placebo‐controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee
por: Majeed, Muhammed, et al.
Publicado: (2019)

An exploratory study of selenium status in healthy individuals and in patients with COVID-19 in a south Indian population: The case for adequate selenium status
por: Majeed, Muhammed, et al.
Publicado: (2021)

A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of a Nutritional Supplement (ImmuActive(TM)) for COVID-19 Patients
por: Majeed, Muhammed, et al.
Publicado: (2021)

Can Selenium Reduce the Susceptibility and Severity of SARS-CoV-2?—A Comprehensive Review
por: Majeed, Muhammed, et al.
Publicado: (2022)

A Short-Term Safety Evaluation of Silbinol(®)- an Extract from Pterocarpus marsupium in Healthy Adults- a Randomized, Double-Blind, Placebo-Controlled Study
por: Majeed, Muhammed, et al.
Publicado: (2023)

Bacillus coagulans MTCC 5856 for the management of major depression with irritable bowel syndrome: a randomised, double-blind, placebo controlled, multi-centre, pilot clinical study
por: Majeed, Muhammed, et al.
Publicado: (2018)

Novel Combinatorial Regimen of Garcinol and Curcuminoids for Non-alcoholic Steatohepatitis (NASH) in Mice
por: Majeed, Muhammed, et al.
Publicado: (2020)

Lesser Investigated Natural Ingredients for the Management of Obesity
por: Majeed, Muhammed, et al.
Publicado: (2021)

Synthesis and Evaluation of the Anti-Oxidant Capacity of Curcumin Glucuronides, the Major Curcumin Metabolites
por: Choudhury, Ambar K., et al.
Publicado: (2015)

A Randomized Double-Blind, Placebo-Controlled Study to Evaluate the Anti-Skin-Aging Effect of LactoSporin – The Extracellular Metabolite from Bacillus coagulans (Weizmannia coagulans) MTCC 5856 in Healthy Female Volunteers
por: Majeed, Muhammed, et al.
Publicado: (2023)

Rapid assessment of viable but non-culturable Bacillus coagulans MTCC 5856 in commercial formulations using Flow cytometry
por: Majeed, Muhammed, et al.
Publicado: (2018)

Clinical Study to Evaluate the Efficacy and Safety of a Hair Serum Product in Healthy Adult Male and Female Volunteers with Hair Fall
por: Majeed, Muhammed, et al.
Publicado: (2020)

The effects of Bacillus coagulans MTCC 5856 on functional gas and bloating in adults: A randomized, double-blind, placebo-controlled study
por: Majeed, Muhammed, et al.
Publicado: (2023)

The Anti-Obesity Potential of Cyperus rotundus Extract Containing Piceatannol, Scirpusin A and Scirpusin B from Rhizomes: Preclinical and Clinical Evaluations
por: Majeed, Muhammed, et al.
Publicado: (2022)

Galactomannan from Trigonella foenum‐graecum L. seed: Prebiotic application and its fermentation by the probiotic Bacillus coagulans strain MTCC 5856
por: Majeed, Muhammed, et al.
Publicado: (2018)

Evaluation of the Safety and Efficacy of a Multienzyme Complex in Patients with Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study
por: Majeed, Muhammed, et al.
Publicado: (2018)

Standardized Emblica officinalis fruit extract inhibited the activities of α‐amylase, α‐glucosidase, and dipeptidyl peptidase‐4 and displayed antioxidant potential
por: Majeed, Muhammed, et al.
Publicado: (2019)

Piceatannol Exerts Anti-Obesity Effects in C57BL/6 Mice through Modulating Adipogenic Proteins and Gut Microbiota
por: Tung, Yen-Chen, et al.
Publicado: (2016)

Targeting beta-Catenin signaling to induce apoptosis in human breast cancer cells by z-Guggulsterone and Gugulipid extract of Ayurvedic medicine plant Commiphora mukul
por: Jiang, Guoqin, et al.
Publicado: (2013)

Boswellia serrata Extract Containing 30% 3-Acetyl-11-Keto-Boswellic Acid Attenuates Inflammatory Mediators and Preserves Extracellular Matrix in Collagen-Induced Arthritis
por: Majeed, Muhammed, et al.
Publicado: (2021)

Investigation of repeated dose (90 day) oral toxicity, reproductive/developmental toxicity and mutagenic potential of ‘Calebin A’
por: Majeed, Muhammed, et al.
Publicado: (2015)

The Cancer Chemopreventive and Therapeutic Potential of Tetrahydrocurcumin
por: Lai, Ching-Shu, et al.
Publicado: (2020)

Efficacy and safety of 1% forskolin eye drops in open angle glaucoma – An open label study
por: Majeed, Muhammed, et al.
Publicado: (2015)

Probiotic modulation of gut microbiota by Bacillus coagulans MTCC 5856 in healthy subjects: A randomized, double-blind, placebo-control study
por: Majeed, Muhammed, et al.
Publicado: (2023)

The Effects of Antioxidants and Pulsed Magnetic Fields on Slow and Fast Skeletal Muscle Atrophy Induced by Streptozotocin: A Preclinical Study
por: Tastekin, Bora, et al.
Publicado: (2023)

Bacillus coagulans MTCC 5856 supplementation in the management of diarrhea predominant Irritable Bowel Syndrome: a double blind randomized placebo controlled pilot clinical study
por: Majeed, Muhammed, et al.
Publicado: (2016)

Chemopreventive effect of natural dietary compounds on xenobiotic-induced toxicity
por: Wu, Jia-Ching, et al.
Publicado: (2016)

Evaluation of genetic and phenotypic consistency of Bacillus coagulans MTCC 5856: a commercial probiotic strain
por: Majeed, Muhammed, et al.
Publicado: (2016)

Reactivity and stability of selected flavor compounds
por: Weerawatanakorn, Monthana, et al.
Publicado: (2015)

A randomized, double-blind clinical trial of a herbal formulation (GlycaCare-II) for the management of type 2 diabetes in comparison with metformin
por: Majeed, Muhammed, et al.
Publicado: (2021)

Disposition, Metabolism and Histone Deacetylase and Acetyltransferase Inhibition Activity of Tetrahydrocurcumin and Other Curcuminoids
por: Novaes, Júlia T., et al.
Publicado: (2017)

Chemopreventive Effects of Phytochemicals and Medicines on M1/M2 Polarized Macrophage Role in Inflammation-Related Diseases
por: Koh, Yen-Chun, et al.
Publicado: (2018)

Genomic Profiling of Patient-Derived Colon Cancer Xenograft Models
por: Lee, Won-Suk, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3kasi5ibo1d50dscev48i2m9jj