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Defects in the Acquisition of Tumor-Killing Capability of CD8(+) Cytotoxic T Cells in Streptozotocin-Induced Diabetic Mice

Emerging evidences have shown that diabetes mellitus not only raises risk but also heightens mortality rate of cancer. It is not clear, however, whether antitumor CD8(+) cytotoxic T lymphocyte (CTL) response is down-modulated in diabetic hosts. We investigated the impact of hyperglycemia on CTLs...

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Detalles Bibliográficos
Autores principales:	Chen, Shu-Ching, Su, Yu-Chia, Lu, Ya-Ting, Ko, Patrick Chow-In, Chang, Pei-Yu, Lin, Hung-Ju, Ho, Hong-Nerng, Lai, Yo-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229103/ https://www.ncbi.nlm.nih.gov/pubmed/25390652 http://dx.doi.org/10.1371/journal.pone.0109961

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