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Epidermal Growth Factor Receptor Inhibition with Erlotinib Partially Prevents Cisplatin-Induced Nephrotoxicity in Rats

The effects of blocking the epidermal growth factor receptor (EGFR) in acute kidney injury (AKI) are controversial. Here we investigated the renoprotective effect of erlotinib, a selective tyrosine kinase inhibitor that can block EGFR activity, on cisplatin (CP)-induced AKI. Groups of animals were g...

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Detalles Bibliográficos
Autores principales:	Wada, Yukihiro, Iyoda, Masayuki, Matsumoto, Kei, Shindo-Hirai, Yuki, Kuno, Yoshihiro, Yamamoto, Yasutaka, Suzuki, Taihei, Saito, Tomohiro, Iseri, Ken, Shibata, Takanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229108/ https://www.ncbi.nlm.nih.gov/pubmed/25390346 http://dx.doi.org/10.1371/journal.pone.0111728

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