The Circadian Clock Maintains Cardiac Function by Regulating Mitochondrial Metabolism in Mice

Cardiac function is highly dependent on oxidative energy, which is produced by mitochondrial respiration. Defects in mitochondrial function are associated with both structural and functional abnormalities in the heart. Here, we show that heart-specific ablation of the circadian clock gene Bmal1 resu...

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Detalles Bibliográficos
Autores principales: Kohsaka, Akira, Das, Partha, Hashimoto, Izumi, Nakao, Tomomi, Deguchi, Yoko, Gouraud, Sabine S., Waki, Hidefumi, Muragaki, Yasuteru, Maeda, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229239/
https://www.ncbi.nlm.nih.gov/pubmed/25389966
http://dx.doi.org/10.1371/journal.pone.0112811

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