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CYLD Negatively Regulates Nontypeable Haemophilus influenzae-Induced IL-8 Expression via Phosphatase MKP-1-Dependent Inhibition of ERK
Nontypeable Haemophilus influenzae (NTHi), a Gram-negative bacterium, is the primary cause of otitis media in children and the exacerbation of chronic obstructive pulmonary disease in adults. A hallmark of both diseases is an overactive inflammatory response, including the upregulation of chemokines...
Autores principales: | Wang, Wenzhuo Y., Komatsu, Kensei, Huang, Yuxian, Wu, Jing, Zhang, Wenhong, Lee, Ji-Yun, Miyata, Masanori, Xu, Haidong, Li, Jian-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229244/ https://www.ncbi.nlm.nih.gov/pubmed/25389768 http://dx.doi.org/10.1371/journal.pone.0112516 |
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