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Characterization of tau oligomeric seeds in progressive supranuclear palsy

BACKGROUND: Progressive supranuclear palsy (PSP) is a neurodegenerative tauopathy which is primarily defined by the deposition of tau into globose-type neurofibrillary tangles (NFT). Tau in its native form has important functions for microtubule dynamics. Tau undergoes alternative splicing in exons...

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Detalles Bibliográficos
Autores principales: Gerson, Julia E, Sengupta, Urmi, Lasagna-Reeves, Cristian A, Guerrero-Muñoz, Marcos J, Troncoso, Juan, Kayed, Rakez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229782/
https://www.ncbi.nlm.nih.gov/pubmed/24927818
http://dx.doi.org/10.1186/2051-5960-2-73