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Characterization of tau oligomeric seeds in progressive supranuclear palsy
BACKGROUND: Progressive supranuclear palsy (PSP) is a neurodegenerative tauopathy which is primarily defined by the deposition of tau into globose-type neurofibrillary tangles (NFT). Tau in its native form has important functions for microtubule dynamics. Tau undergoes alternative splicing in exons...
Autores principales: | Gerson, Julia E, Sengupta, Urmi, Lasagna-Reeves, Cristian A, Guerrero-Muñoz, Marcos J, Troncoso, Juan, Kayed, Rakez |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229782/ https://www.ncbi.nlm.nih.gov/pubmed/24927818 http://dx.doi.org/10.1186/2051-5960-2-73 |
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