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Loss of histone H4K20 trimethylation predicts poor prognosis in breast cancer and is associated with invasive activity

INTRODUCTION: Loss of histone H4 lysine 20 trimethylation (H4K20me3) is associated with multiple cancers, but its role in breast tumors is unclear. In addition, the pathological effects of global reduction in H4K20me3 remain mostly unknown. Therefore, a major goal of this study was to elucidate the...

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Detalles Bibliográficos
Autores principales:	Yokoyama, Yuhki, Matsumoto, Ayaka, Hieda, Miki, Shinchi, Yoshimi, Ogihara, Eri, Hamada, Mai, Nishioka, Yu, Kimura, Hiroshi, Yoshidome, Katsuhide, Tsujimoto, Masahiko, Matsuura, Nariaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229880/ https://www.ncbi.nlm.nih.gov/pubmed/24953066 http://dx.doi.org/10.1186/bcr3681

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