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A statistical approach for inferring the 3D structure of the genome
Motivation: Recent technological advances allow the measurement, in a single Hi-C experiment, of the frequencies of physical contacts among pairs of genomic loci at a genome-wide scale. The next challenge is to infer, from the resulting DNA–DNA contact maps, accurate 3D models of how chromosomes fol...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229903/ https://www.ncbi.nlm.nih.gov/pubmed/24931992 http://dx.doi.org/10.1093/bioinformatics/btu268 |