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Tau pathology does not affect experience-driven single-neuron and network-wide Arc/Arg3.1 responses

Intraneuronal neurofibrillary tangles (NFTs) – a characteristic pathological feature of Alzheimer’s and several other neurodegenerative diseases – are considered a major target for drug development. Tangle load correlates well with the severity of cognitive symptoms and mouse models of tauopathy are...

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Detalles Bibliográficos
Autores principales:	Rudinskiy, Nikita, Hawkes, Jonathan M, Wegmann, Susanne, Kuchibhotla, Kishore V, Muzikansky, Alona, Betensky, Rebecca A, Spires-Jones, Tara L, Hyman, Bradley T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229905/ https://www.ncbi.nlm.nih.gov/pubmed/24915991 http://dx.doi.org/10.1186/2051-5960-2-63

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