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Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study

Numerous studies have implicated the abnormal accumulation of intraneuronal amyloid-β (Aβ) as an important contributor to Alzheimer’s disease (AD) pathology, capable of triggering neuroinflammation, tau hyperphosphorylation and cognitive deficits. However, the occurrence and pathological relevance o...

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Detalles Bibliográficos
Autores principales:	Iulita, M Florencia, Allard, Simon, Richter, Luise, Munter, Lisa-Marie, Ducatenzeiler, Adriana, Weise, Christoph, Do Carmo, Sonia, Klein, William L, Multhaup, Gerhard, Cuello, A Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229908/ https://www.ncbi.nlm.nih.gov/pubmed/24903713 http://dx.doi.org/10.1186/2051-5960-2-61

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