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Graph analysis of β(2) adrenergic receptor structures: a “social network” of GPCR residues

PURPOSE: G protein-coupled receptors (GPCRs) are a superfamily of membrane proteins of vast pharmaceutical interest. Here, we describe a graph theory-based analysis of the structure of the β(2) adrenergic receptor (β(2) AR), a prototypical GPCR. In particular, we illustrate the network of direct and...

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Detalles Bibliográficos
Autores principales:	Sheftel, Samuel, Muratore, Kathryn E, Black, Michael, Costanzi, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230308/ https://www.ncbi.nlm.nih.gov/pubmed/25505660 http://dx.doi.org/10.1186/2193-9616-1-16

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