Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells

Circulating tumor cells (CTCs) are shed from primary tumors into the bloodstream, mediating the hematogenous spread of cancer to distant organs. To define their composition, we compared genome-wide expression profiles of CTCs with matched primary tumors in a mouse model of pancreatic cancer, isolati...

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Detalles Bibliográficos
Autores principales: Ting, David T., Wittner, Ben S., Ligorio, Matteo, Jordan, Nicole Vincent, Shah, Ajay M., Miyamoto, David T., Aceto, Nicola, Bersani, Francesca, Brannigan, Brian W., Xega, Kristina, Ciciliano, Jordan C., Zhu, Huili, MacKenzie, Olivia C., Trautwein, Julie, Arora, Kshitij S., Shahid, Mohammad, Ellis, Haley L., Qu, Na, Bardeesy, Nabeel, Rivera, Miguel N., Deshpande, Vikram, Ferrone, Cristina R., Kapur, Ravi, Ramaswamy, Sridhar, Shioda, Toshi, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230325/
https://www.ncbi.nlm.nih.gov/pubmed/25242334
http://dx.doi.org/10.1016/j.celrep.2014.08.029

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