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Polylysine-Mediated Translocation of the Diphtheria Toxin Catalytic Domain through the Anthrax Protective Antigen Pore

[Image: see text] The protective antigen (PA) moiety of anthrax toxin forms oligomeric pores in the endosomal membrane, which translocate the effector proteins of the toxin to the cytosol. Effector proteins bind to oligomeric PA via their respective N-terminal domains and undergo N- to C-terminal tr...

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Detalles Bibliográficos
Autores principales: Sharma, Onkar, Collier, R. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230326/
https://www.ncbi.nlm.nih.gov/pubmed/25317832
http://dx.doi.org/10.1021/bi500985v