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Differential regulation of MAGE-A1 promoter activity by BORIS and Sp1, both interacting with the TATA binding protein

BACKGROUND: As cancer-testis MAGE-A antigens are targets for tumor immunotherapy, it is important to study the regulation of their expression in cancers. This regulation appears to be rather complex and at the moment controversial. Although it is generally accepted that MAGE-A expression is controll...

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Detalles Bibliográficos
Autores principales: Schwarzenbach, Heidi, Eichelser, Corinna, Steinbach, Bettina, Tadewaldt, Josefine, Pantel, Klaus, Lobanenkov, Victor, Loukinov, Dmitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230356/
https://www.ncbi.nlm.nih.gov/pubmed/25363021
http://dx.doi.org/10.1186/1471-2407-14-796