Generation of multi-gene knockout rabbits using the Cas9/gRNA system

The prokaryotic clustered regularly interspaced short palindromic repeat (CRISPR)-associated system (Cas) is a simple, robust and efficient technique for gene targeting in model organisms such as zebrafish, mice and rats. In this report, we applied CRISPR technology to rabbits by microinjection of C...

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Detalles Bibliográficos
Autores principales: Yan, Quanmei, Zhang, Quanjun, Yang, Huaqiang, Zou, Qingjian, Tang, Chengcheng, Fan, Nana, Lai, Liangxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230364/
https://www.ncbi.nlm.nih.gov/pubmed/25408890
http://dx.doi.org/10.1186/2045-9769-3-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230364/
https://www.ncbi.nlm.nih.gov/pubmed/25408890
http://dx.doi.org/10.1186/2045-9769-3-12

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