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Distinct HIV-1 entry phenotypes are associated with transmission, subtype specificity, and resistance to broadly neutralizing antibodies

BACKGROUND: The efficiency of CD4/CCR5 mediated HIV-1 entry has important implications for pathogenesis and transmission. The HIV-1 receptor affinity profiling (Affinofile) system analyzes and quantifies the infectivity of HIV-1 envelopes (Envs) across a spectrum of CD4/CCR5 expression levels and di...

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Detalles Bibliográficos
Autores principales:	Chikere, Kelechi, Webb, Nicholas E, Chou, Tom, Borm, Katharina, Sterjovski, Jasminka, Gorry, Paul R, Lee, Benhur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230403/ https://www.ncbi.nlm.nih.gov/pubmed/24957778 http://dx.doi.org/10.1186/1742-4690-11-48

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