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The quantified cell
The microscopic world of a cell can be as alien to our human-centered intuition as the confinement of quarks within protons or the event horizon of a black hole. We are prone to thinking by analogy—Golgi cisternae stack like pancakes, red blood cells look like donuts—but very little in our human exp...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230611/ https://www.ncbi.nlm.nih.gov/pubmed/25368429 http://dx.doi.org/10.1091/mbc.E14-09-1347 |
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author | Flamholz, Avi Phillips, Rob Milo, Ron |
author_facet | Flamholz, Avi Phillips, Rob Milo, Ron |
author_sort | Flamholz, Avi |
collection | PubMed |
description | The microscopic world of a cell can be as alien to our human-centered intuition as the confinement of quarks within protons or the event horizon of a black hole. We are prone to thinking by analogy—Golgi cisternae stack like pancakes, red blood cells look like donuts—but very little in our human experience is truly comparable to the immensely crowded, membrane-subdivided interior of a eukaryotic cell or the intricately layered structures of a mammalian tissue. So in our daily efforts to understand how cells work, we are faced with a challenge: how do we develop intuition that works at the microscopic scale? |
format | Online Article Text |
id | pubmed-4230611 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The American Society for Cell Biology |
record_format | MEDLINE/PubMed |
spelling | pubmed-42306112015-01-20 The quantified cell Flamholz, Avi Phillips, Rob Milo, Ron Mol Biol Cell Perspectives The microscopic world of a cell can be as alien to our human-centered intuition as the confinement of quarks within protons or the event horizon of a black hole. We are prone to thinking by analogy—Golgi cisternae stack like pancakes, red blood cells look like donuts—but very little in our human experience is truly comparable to the immensely crowded, membrane-subdivided interior of a eukaryotic cell or the intricately layered structures of a mammalian tissue. So in our daily efforts to understand how cells work, we are faced with a challenge: how do we develop intuition that works at the microscopic scale? The American Society for Cell Biology 2014-11-05 /pmc/articles/PMC4230611/ /pubmed/25368429 http://dx.doi.org/10.1091/mbc.E14-09-1347 Text en © 2014 Flamholz et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0). “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology. |
spellingShingle | Perspectives Flamholz, Avi Phillips, Rob Milo, Ron The quantified cell |
title | The quantified cell |
title_full | The quantified cell |
title_fullStr | The quantified cell |
title_full_unstemmed | The quantified cell |
title_short | The quantified cell |
title_sort | quantified cell |
topic | Perspectives |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230611/ https://www.ncbi.nlm.nih.gov/pubmed/25368429 http://dx.doi.org/10.1091/mbc.E14-09-1347 |
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