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TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion

Recent studies implicate a role for cell mechanics in cancer progression. The epithelial-to-mesenchymal transition (EMT) regulates the detachment of cancer cells from the epithelium and facilitates their invasion into stromal tissue. Although classic EMT hallmarks include loss of cell–cell adhesions...

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Detalles Bibliográficos
Autores principales:	Osborne, Lukas D., Li, George Z., How, Tam, O'Brien, E. Tim, Blobe, Gerard C., Superfine, Richard, Mythreye, Karthikeyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230614/ https://www.ncbi.nlm.nih.gov/pubmed/25143398 http://dx.doi.org/10.1091/mbc.E14-05-1015

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