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Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin
A long-standing issue in the field of signal transduction is to understand the cross-talk between receptor tyrosine kinases (RTKs) and heterotrimeric G proteins, two major and distinct signaling hubs that control eukaryotic cell behavior. Although stimulation of many RTKs leads to activation of trim...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230624/ https://www.ncbi.nlm.nih.gov/pubmed/25187647 http://dx.doi.org/10.1091/mbc.E14-05-0978 |