Cargando…

Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease

Inflammatory bowel diseases can commonly present many cutaneous lesions which can contribute to the diagnosis of the disease or its activity. The most frequent cutaneous or mucocutaneous manifestations suggesting ulcerative rectocolitis activity are erythema nodosum (3-10%), pyoderma gangrenosum (5-...

Descripción completa

Detalles Bibliográficos
Autores principales: Komatsu, Yumi Cristina, Capareli, Gabriela Cunha, Boin, Maria Fernanda Feitosa de Camargo, Lellis, Rute, de Freitas, Thaís Helena Proença, Simone, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230667/
https://www.ncbi.nlm.nih.gov/pubmed/25387503
http://dx.doi.org/10.1590/abd1806-4841.20143001
_version_ 1782344312558714880
author Komatsu, Yumi Cristina
Capareli, Gabriela Cunha
Boin, Maria Fernanda Feitosa de Camargo
Lellis, Rute
de Freitas, Thaís Helena Proença
Simone, Karine
author_facet Komatsu, Yumi Cristina
Capareli, Gabriela Cunha
Boin, Maria Fernanda Feitosa de Camargo
Lellis, Rute
de Freitas, Thaís Helena Proença
Simone, Karine
author_sort Komatsu, Yumi Cristina
collection PubMed
description Inflammatory bowel diseases can commonly present many cutaneous lesions which can contribute to the diagnosis of the disease or its activity. The most frequent cutaneous or mucocutaneous manifestations suggesting ulcerative rectocolitis activity are erythema nodosum (3-10%), pyoderma gangrenosum (5-12%) and aphthous stomatitis (4%). Other reactive skin manifestations related to immunological mechanisms associated with the inflammatory bowel disease are: Sweet's syndrome, arthritis-dermatitis syndrome associated with inflammatory bowel disease and leukocytoclastic vasculitis. We describe the case of a young man with diagnosis of ulcerative rectocolitis, which presented an extensive cutaneous gangrene secondary to microvascular thrombosis. The case represents a dermatologic rarity and should be recognized as a cutaneous manifestation related to the hypercoagulability state observed in the disease's activity.
format Online
Article
Text
id pubmed-4230667
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Sociedade Brasileira de Dermatologia
record_format MEDLINE/PubMed
spelling pubmed-42306672014-11-14 Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease Komatsu, Yumi Cristina Capareli, Gabriela Cunha Boin, Maria Fernanda Feitosa de Camargo Lellis, Rute de Freitas, Thaís Helena Proença Simone, Karine An Bras Dermatol Case Report Inflammatory bowel diseases can commonly present many cutaneous lesions which can contribute to the diagnosis of the disease or its activity. The most frequent cutaneous or mucocutaneous manifestations suggesting ulcerative rectocolitis activity are erythema nodosum (3-10%), pyoderma gangrenosum (5-12%) and aphthous stomatitis (4%). Other reactive skin manifestations related to immunological mechanisms associated with the inflammatory bowel disease are: Sweet's syndrome, arthritis-dermatitis syndrome associated with inflammatory bowel disease and leukocytoclastic vasculitis. We describe the case of a young man with diagnosis of ulcerative rectocolitis, which presented an extensive cutaneous gangrene secondary to microvascular thrombosis. The case represents a dermatologic rarity and should be recognized as a cutaneous manifestation related to the hypercoagulability state observed in the disease's activity. Sociedade Brasileira de Dermatologia 2014 /pmc/articles/PMC4230667/ /pubmed/25387503 http://dx.doi.org/10.1590/abd1806-4841.20143001 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Komatsu, Yumi Cristina
Capareli, Gabriela Cunha
Boin, Maria Fernanda Feitosa de Camargo
Lellis, Rute
de Freitas, Thaís Helena Proença
Simone, Karine
Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease
title Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease
title_full Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease
title_fullStr Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease
title_full_unstemmed Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease
title_short Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease
title_sort skin gangrene as an extraintestinal manifestation of inflammatory bowel disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230667/
https://www.ncbi.nlm.nih.gov/pubmed/25387503
http://dx.doi.org/10.1590/abd1806-4841.20143001
work_keys_str_mv AT komatsuyumicristina skingangreneasanextraintestinalmanifestationofinflammatoryboweldisease
AT capareligabrielacunha skingangreneasanextraintestinalmanifestationofinflammatoryboweldisease
AT boinmariafernandafeitosadecamargo skingangreneasanextraintestinalmanifestationofinflammatoryboweldisease
AT lellisrute skingangreneasanextraintestinalmanifestationofinflammatoryboweldisease
AT defreitasthaishelenaproenca skingangreneasanextraintestinalmanifestationofinflammatoryboweldisease
AT simonekarine skingangreneasanextraintestinalmanifestationofinflammatoryboweldisease