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Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease
Inflammatory bowel diseases can commonly present many cutaneous lesions which can contribute to the diagnosis of the disease or its activity. The most frequent cutaneous or mucocutaneous manifestations suggesting ulcerative rectocolitis activity are erythema nodosum (3-10%), pyoderma gangrenosum (5-...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Dermatologia
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230667/ https://www.ncbi.nlm.nih.gov/pubmed/25387503 http://dx.doi.org/10.1590/abd1806-4841.20143001 |
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author | Komatsu, Yumi Cristina Capareli, Gabriela Cunha Boin, Maria Fernanda Feitosa de Camargo Lellis, Rute de Freitas, Thaís Helena Proença Simone, Karine |
author_facet | Komatsu, Yumi Cristina Capareli, Gabriela Cunha Boin, Maria Fernanda Feitosa de Camargo Lellis, Rute de Freitas, Thaís Helena Proença Simone, Karine |
author_sort | Komatsu, Yumi Cristina |
collection | PubMed |
description | Inflammatory bowel diseases can commonly present many cutaneous lesions which can contribute to the diagnosis of the disease or its activity. The most frequent cutaneous or mucocutaneous manifestations suggesting ulcerative rectocolitis activity are erythema nodosum (3-10%), pyoderma gangrenosum (5-12%) and aphthous stomatitis (4%). Other reactive skin manifestations related to immunological mechanisms associated with the inflammatory bowel disease are: Sweet's syndrome, arthritis-dermatitis syndrome associated with inflammatory bowel disease and leukocytoclastic vasculitis. We describe the case of a young man with diagnosis of ulcerative rectocolitis, which presented an extensive cutaneous gangrene secondary to microvascular thrombosis. The case represents a dermatologic rarity and should be recognized as a cutaneous manifestation related to the hypercoagulability state observed in the disease's activity. |
format | Online Article Text |
id | pubmed-4230667 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-42306672014-11-14 Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease Komatsu, Yumi Cristina Capareli, Gabriela Cunha Boin, Maria Fernanda Feitosa de Camargo Lellis, Rute de Freitas, Thaís Helena Proença Simone, Karine An Bras Dermatol Case Report Inflammatory bowel diseases can commonly present many cutaneous lesions which can contribute to the diagnosis of the disease or its activity. The most frequent cutaneous or mucocutaneous manifestations suggesting ulcerative rectocolitis activity are erythema nodosum (3-10%), pyoderma gangrenosum (5-12%) and aphthous stomatitis (4%). Other reactive skin manifestations related to immunological mechanisms associated with the inflammatory bowel disease are: Sweet's syndrome, arthritis-dermatitis syndrome associated with inflammatory bowel disease and leukocytoclastic vasculitis. We describe the case of a young man with diagnosis of ulcerative rectocolitis, which presented an extensive cutaneous gangrene secondary to microvascular thrombosis. The case represents a dermatologic rarity and should be recognized as a cutaneous manifestation related to the hypercoagulability state observed in the disease's activity. Sociedade Brasileira de Dermatologia 2014 /pmc/articles/PMC4230667/ /pubmed/25387503 http://dx.doi.org/10.1590/abd1806-4841.20143001 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Komatsu, Yumi Cristina Capareli, Gabriela Cunha Boin, Maria Fernanda Feitosa de Camargo Lellis, Rute de Freitas, Thaís Helena Proença Simone, Karine Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease |
title | Skin gangrene as an extraintestinal manifestation of inflammatory bowel
disease |
title_full | Skin gangrene as an extraintestinal manifestation of inflammatory bowel
disease |
title_fullStr | Skin gangrene as an extraintestinal manifestation of inflammatory bowel
disease |
title_full_unstemmed | Skin gangrene as an extraintestinal manifestation of inflammatory bowel
disease |
title_short | Skin gangrene as an extraintestinal manifestation of inflammatory bowel
disease |
title_sort | skin gangrene as an extraintestinal manifestation of inflammatory bowel
disease |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230667/ https://www.ncbi.nlm.nih.gov/pubmed/25387503 http://dx.doi.org/10.1590/abd1806-4841.20143001 |
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