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Two cases of renal cell cancer during immunobiologic therapy for psoriasis
Immunobiologic therapy is indicated for severe forms of psoriasis, resistant to conventional therapy. There is growing concern about their safety profile and possible association with cancer development. This article documents two cases of renal cell cancer during treatment with biologic therapy, re...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Dermatologia
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230681/ https://www.ncbi.nlm.nih.gov/pubmed/25387517 http://dx.doi.org/10.1590/abd1806-4841.20143257 |
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author | Zarur, Fabiana Palmieri d'Almeida, Luiza Ferreira Vieira Mafort, Monique Samy Pamplona de Gusmão, Paula Regazzi Avelleira, João Carlos Regazzi |
author_facet | Zarur, Fabiana Palmieri d'Almeida, Luiza Ferreira Vieira Mafort, Monique Samy Pamplona de Gusmão, Paula Regazzi Avelleira, João Carlos Regazzi |
author_sort | Zarur, Fabiana Palmieri |
collection | PubMed |
description | Immunobiologic therapy is indicated for severe forms of psoriasis, resistant to conventional therapy. There is growing concern about their safety profile and possible association with cancer development. This article documents two cases of renal cell cancer during treatment with biologic therapy, reviewing what is described in the literature . The risk of solid tumors as a complication of using TNF-alpha inhibitors is controversial. No conclusion can be drawn from the data in the literature, however, we believe that special attention should be given to those with known risk factors for a specific neoplasm. |
format | Online Article Text |
id | pubmed-4230681 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-42306812014-11-14 Two cases of renal cell cancer during immunobiologic therapy for psoriasis Zarur, Fabiana Palmieri d'Almeida, Luiza Ferreira Vieira Mafort, Monique Samy Pamplona de Gusmão, Paula Regazzi Avelleira, João Carlos Regazzi An Bras Dermatol Communication Immunobiologic therapy is indicated for severe forms of psoriasis, resistant to conventional therapy. There is growing concern about their safety profile and possible association with cancer development. This article documents two cases of renal cell cancer during treatment with biologic therapy, reviewing what is described in the literature . The risk of solid tumors as a complication of using TNF-alpha inhibitors is controversial. No conclusion can be drawn from the data in the literature, however, we believe that special attention should be given to those with known risk factors for a specific neoplasm. Sociedade Brasileira de Dermatologia 2014 /pmc/articles/PMC4230681/ /pubmed/25387517 http://dx.doi.org/10.1590/abd1806-4841.20143257 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Communication Zarur, Fabiana Palmieri d'Almeida, Luiza Ferreira Vieira Mafort, Monique Samy Pamplona de Gusmão, Paula Regazzi Avelleira, João Carlos Regazzi Two cases of renal cell cancer during immunobiologic therapy for psoriasis |
title | Two cases of renal cell cancer during immunobiologic therapy for
psoriasis
|
title_full | Two cases of renal cell cancer during immunobiologic therapy for
psoriasis
|
title_fullStr | Two cases of renal cell cancer during immunobiologic therapy for
psoriasis
|
title_full_unstemmed | Two cases of renal cell cancer during immunobiologic therapy for
psoriasis
|
title_short | Two cases of renal cell cancer during immunobiologic therapy for
psoriasis
|
title_sort | two cases of renal cell cancer during immunobiologic therapy for
psoriasis |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230681/ https://www.ncbi.nlm.nih.gov/pubmed/25387517 http://dx.doi.org/10.1590/abd1806-4841.20143257 |
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