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A flexible Bayesian method for detecting allelic imbalance in RNA-seq data

BACKGROUND: One method of identifying cis regulatory differences is to analyze allele-specific expression (ASE) and identify cases of allelic imbalance (AI). RNA-seq is the most common way to measure ASE and a binomial test is often applied to determine statistical significance of AI. This implicitl...

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Detalles Bibliográficos
Autores principales:	León-Novelo, Luis G, McIntyre, Lauren M, Fear, Justin M, Graze, Rita M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230747/ https://www.ncbi.nlm.nih.gov/pubmed/25339465 http://dx.doi.org/10.1186/1471-2164-15-920

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