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Cbx2 stably associates with mitotic chromosomes via a PRC2- or PRC1-independent mechanism and is needed for recruiting PRC1 complex to mitotic chromosomes
Polycomb group (PcG) proteins are epigenetic transcriptional factors that repress key developmental regulators and maintain cellular identity through mitosis via a poorly understood mechanism. Using quantitative live-cell imaging in mouse ES cells and tumor cells, we demonstrate that, although Polyc...
Autores principales: | Zhen, Chao Yu, Duc, Huy Nguyen, Kokotovic, Marko, Phiel, Christopher J., Ren, Xiaojun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230780/ https://www.ncbi.nlm.nih.gov/pubmed/25232004 http://dx.doi.org/10.1091/mbc.E14-06-1109 |
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