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Cbx2 stably associates with mitotic chromosomes via a PRC2- or PRC1-independent mechanism and is needed for recruiting PRC1 complex to mitotic chromosomes

Polycomb group (PcG) proteins are epigenetic transcriptional factors that repress key developmental regulators and maintain cellular identity through mitosis via a poorly understood mechanism. Using quantitative live-cell imaging in mouse ES cells and tumor cells, we demonstrate that, although Polyc...

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Detalles Bibliográficos
Autores principales: Zhen, Chao Yu, Duc, Huy Nguyen, Kokotovic, Marko, Phiel, Christopher J., Ren, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230780/
https://www.ncbi.nlm.nih.gov/pubmed/25232004
http://dx.doi.org/10.1091/mbc.E14-06-1109

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