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Inhibition of ESCRT-II–CHMP6 interactions impedes cytokinetic abscission and leads to cell death
Recently the ESCRT-III filamentous complex was designated as the driving force for mammalian cell abscission, that is, fission of the intercellular membrane bridge connecting daughter cells at the end of cytokinesis. However, how ESCRT-III is activated to set on abscission has not been resolved. Her...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230781/ https://www.ncbi.nlm.nih.gov/pubmed/25232011 http://dx.doi.org/10.1091/mbc.E14-08-1317 |