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Inhibition of ESCRT-II–CHMP6 interactions impedes cytokinetic abscission and leads to cell death

Recently the ESCRT-III filamentous complex was designated as the driving force for mammalian cell abscission, that is, fission of the intercellular membrane bridge connecting daughter cells at the end of cytokinesis. However, how ESCRT-III is activated to set on abscission has not been resolved. Her...

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Detalles Bibliográficos
Autores principales: Goliand, Inna, Nachmias, Dikla, Gershony, Ofir, Elia, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230781/
https://www.ncbi.nlm.nih.gov/pubmed/25232011
http://dx.doi.org/10.1091/mbc.E14-08-1317