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Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation
The pathways driving desmosome and adherens junction assembly are temporally and spatially coordinated, but how they are functionally coupled is poorly understood. Here we show that the Armadillo protein plakophilin 3 (Pkp3) mediates both desmosome assembly and E-cadherin maturation through Rap1 GTP...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230782/ https://www.ncbi.nlm.nih.gov/pubmed/25208567 http://dx.doi.org/10.1091/mbc.E14-05-0968 |