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Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation

The pathways driving desmosome and adherens junction assembly are temporally and spatially coordinated, but how they are functionally coupled is poorly understood. Here we show that the Armadillo protein plakophilin 3 (Pkp3) mediates both desmosome assembly and E-cadherin maturation through Rap1 GTP...

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Detalles Bibliográficos
Autores principales: Todorovic´, Viktor, Koetsier, Jennifer L., Godsel, Lisa M., Green, Kathleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230782/
https://www.ncbi.nlm.nih.gov/pubmed/25208567
http://dx.doi.org/10.1091/mbc.E14-05-0968