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A framework incorporating the impact of exposure scenarios and application conditions on risk assessment of chemicals applied to skin
PURPOSE: 1. To develop a framework for exposure calculation via the dermal route to meet the needs of 21st century toxicity testing and refine current approaches; 2. To demonstrate the impact of exposure scenario and application conditions on the plasma concentration following dermal exposure. METHO...
Autores principales: | Dancik, Yuri, Troutman, John A, Jaworska, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230815/ https://www.ncbi.nlm.nih.gov/pubmed/25505655 http://dx.doi.org/10.1186/2193-9616-1-10 |
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