Cargando…

I(f) current channel inhibitor (ivabradine) deserves cardioprotective effect via down-regulating the expression of matrix metalloproteinase (MMP)-2 and attenuating apoptosis in diabetic mice

BACKGROUND: Ivabradine (IVBD), a novel I(f)-channel inhibitor and specific heart rate-lowering agent, is known to have anti-oxidative activity that promotes endothelial function. However, the molecular mechanism through which IVBD acts on cardiac function has yet to be elucidated, especially in expe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Shao-Liang, Hu, Zuo-Ying, Zuo, Guang-Feng, Li, Ming-Hui, Li, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230832/ https://www.ncbi.nlm.nih.gov/pubmed/25361902 http://dx.doi.org/10.1186/1471-2261-14-150

Ejemplares similares

Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection
por: Bencsik, Péter, et al.
Publicado: (2018)

Cardioprotective Effect of Novel Matrix Metalloproteinase Inhibitors
por: Gömöri, Kamilla, et al.
Publicado: (2020)

Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
por: Hur, J. H., et al.
Publicado: (2000)

Expression and function of matrix metalloproteinase (MMP)-28
por: Rodgers, Ursula R., et al.
Publicado: (2009)

Quantification of matrix metalloproteinases MMP-8 and MMP-9 in gingival overgrowth
por: Orozco-Páez, Jennifer, et al.
Publicado: (2021)

Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma.
por: Kim, T. S., et al.
Publicado: (1999)

The Significance of Matrix Metalloproteinase 9 (MMP-9) and Metalloproteinase 2 (MMP-2) in Urinary Bladder Cancer
por: Kudelski, Jacek, et al.
Publicado: (2023)

Role of Matrix Metalloproteinase (MMP) 2 and MMP-9 in Soft Tissue Sarcoma
por: Yang, Hyun Kee, et al.
Publicado: (2014)

Matrix metalloproteinases (MMP’s) in the rat scoliotic intervertebral disc
por: Grivas, Theodoros B, et al.
Publicado: (2010)

Klotho Protein Reduced the Expression of Matrix Metalloproteinase-1 (MMP-1) and Matrix Metalloproteinase-3 (MMP-3) in Fibroblasts from Patients with Pelvic Organ Prolapse (POP) by Down-Regulating the Phosphorylation of ERK1/2
por: Qiu, Jun, et al.
Publicado: (2019)

Matrix Metalloproteinases in Oral Health—Special Attention on MMP-8
por: Atanasova, Tsvetelina, et al.
Publicado: (2023)

The Role of Matrix Metalloproteinases (MMP-8, MMP-9, MMP-13) in Periodontal and Peri-Implant Pathological Processes
por: Luchian, Ionut, et al.
Publicado: (2022)

Enhanced Expression but Decreased Specific Activity of Matrix Metalloproteinase 10 (MMP-10) in Comparison with Matrix Metalloproteinase 3 (MMP-3) in Human Urinary Bladder Carcinoma
por: Kudelski, Jacek, et al.
Publicado: (2021)

Matrix Metalloproteinases MMP-2 and MMP-9 Occupy a New Role in Severe Preeclampsia
por: Timokhina, Elena, et al.
Publicado: (2020)

Melatonin attenuates angiotensin II-induced abdominal aortic aneurysm through the down-regulation of matrix metalloproteinases
por: Kong, Jing, et al.
Publicado: (2017)

Cardioprotective Effects of Voluntary Exercise in a Rat Model: Role of Matrix Metalloproteinase-2
por: Pósa, Anikó, et al.
Publicado: (2015)

Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma
por: Talvensaari-Mattila, A, et al.
Publicado: (2003)

Matrix Metalloproteinase-9 (MMP-9) Gene Polymorphism in Stroke Patients
por: Buraczynska, Kinga, et al.
Publicado: (2015)

Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas
por: Ramachandran, Rahimsan K., et al.
Publicado: (2017)

New insights into the role of matrix metalloproteinase 3 (MMP3) in bone
por: Jehan, Frédéric, et al.
Publicado: (2022)

Matrix metalloproteinase-3 (MMP-3)–mediated gene therapy for glaucoma
por: O’Callaghan, Jeffrey, et al.
Publicado: (2023)

Novel Matrix Metalloproteinase-9 (MMP-9) Inhibitors in Cancer Treatment
por: Rashid, Zainab Ahmed, et al.
Publicado: (2023)

Matrix Metalloproteinase-9 (MMP-9) as a Cancer Biomarker and MMP-9 Biosensors: Recent Advances
por: Huang, Hao
Publicado: (2018)

Selected Matrix Metalloproteinases (MMP-2, MMP-7) and Their Inhibitor (TIMP-2) in Adult and Pediatric Cancer
por: Kaczorowska, Aleksandra, et al.
Publicado: (2020)

Altered Maternal Serum Matrix Metalloproteinases MMP-2, MMP-3, MMP-9, and MMP-13 in Severe Early- and Late-Onset Preeclampsia
por: Laskowska, Marzena
Publicado: (2017)

Interleukin-6 increases matrix metalloproteinase-14 (MMP-14) levels via down-regulation of p53 to drive cancer progression
por: Cathcart, Jillian M., et al.
Publicado: (2016)

Associations of matrix metalloproteinase (MMP)-8, MMP-9, and their inhibitor, tissue inhibitor of metalloproteinase-1, with obesity-related biomarkers in apparently healthy adolescent boys
por: Shin, Youn Ho, et al.
Publicado: (2014)

Matrix Metalloproteinase-2 Inhibition in Acute Ischemia-Reperfusion Heart Injury—Cardioprotective Properties of Carvedilol
por: Skrzypiec-Spring, Monika, et al.
Publicado: (2021)

Quercetin Inhibits the Migration and Invasion of HCCLM3 Cells by Suppressing the Expression of p-Akt1, Matrix Metalloproteinase (MMP) MMP-2, and MMP-9
por: Lu, Jun, et al.
Publicado: (2018)

Inflammation and matrix metalloproteinase 9 (Mmp‐9) regulate photoreceptor regeneration in adult zebrafish
por: Silva, Nicholas J., et al.
Publicado: (2020)

Help for the Deserving
por: Lewisburg, J. H. M.
Publicado: (1876)

Tissue levels of matrix metalloproteinases MMP-2 and MMP-9 are related to the overall survival of patients with gastric carcinoma.
por: Sier, C. F., et al.
Publicado: (1996)

Levels of plasma matrix metalloproteinases (MMP-2 and MMP-9) in response to INTEGRA(®) dermal regeneration template implantation
por: Nessler, MichałBohdan, et al.
Publicado: (2014)

Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryo
por: Blanco, María José, et al.
Publicado: (2017)

Natural Marine and Terrestrial Compounds as Modulators of Matrix Metalloproteinases-2 (MMP-2) and MMP-9 in Alzheimer’s Disease
por: Ciccone, Lidia, et al.
Publicado: (2021)

Dynamic Expression of Membrane Type 1-Matrix Metalloproteinase (Mt1-mmp/Mmp14) in the Mouse Embryo
por: Muñoz-Sáez, Emma, et al.
Publicado: (2021)

Expressions of Matrix Metalloproteinases (MMP-2, MMP-7, and MMP-9) and Their Inhibitors (TIMP-1, TIMP-2) in Inflammatory Bowel Diseases
por: Jakubowska, Katarzyna, et al.
Publicado: (2016)

Matrix Metalloproteinase-9 (MMP-9) polymorphisms in patients with cutaneous malignant melanoma
por: Cotignola, Javier, et al.
Publicado: (2007)

MMpI: A WideRange of Available Compounds of Matrix Metalloproteinase Inhibitors
por: Muvva, Charuvaka, et al.
Publicado: (2016)

Matrix metalloproteinases (MMP) 3 and 9 as biomarkers of severity in COVID-19 patients
por: Gelzo, Monica, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cn1h7uovek7vmgjo3fubef1dre