Clonal Architectures and Driver Mutations in Metastatic Melanomas

To reveal the clonal architecture of melanoma and associated driver mutations, whole genome sequencing (WGS) and targeted extension sequencing were used to characterize 124 melanoma cases. Significantly mutated gene analysis using 13 WGS cases and 15 additional paired extension cases identified know...

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Detalles Bibliográficos
Autores principales: Ding, Li, Kim, Minjung, Kanchi, Krishna L., Dees, Nathan D., Lu, Charles, Griffith, Malachi, Fenstermacher, David, Sung, Hyeran, Miller, Christopher A., Goetz, Brian, Wendl, Michael C., Griffith, Obi, Cornelius, Lynn A., Linette, Gerald P., McMichael, Joshua F., Sondak, Vernon K., Fields, Ryan C., Ley, Timothy J., Mulé, James J., Wilson, Richard K., Weber, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230926/
https://www.ncbi.nlm.nih.gov/pubmed/25393105
http://dx.doi.org/10.1371/journal.pone.0111153

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