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Aging Increases the Susceptivity of MSCs to Reactive Oxygen Species and Impairs Their Therapeutic Potency for Myocardial Infarction
Myocardial infarction (MI) is one of the leading causes of death worldwide and Mesenchymal Stem Cells (MSCs) transplantation has been considered a promising therapy. Recently, it was reported that the therapeutic effectiveness of MSCs is dependent on the age of the donor, yet the underlying mechanis...
Autores principales: | Li, Liang, Guo, Yingfei, Zhai, Hongxia, Yin, Yaxin, Zhang, Jinjin, Chen, Haiwei, Wang, Lei, Li, Na, Liu, Runmei, Xia, Yunfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230939/ https://www.ncbi.nlm.nih.gov/pubmed/25393016 http://dx.doi.org/10.1371/journal.pone.0111850 |
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