Gait Analysis in a Mecp2 Knockout Mouse Model of Rett Syndrome Reveals Early-Onset and Progressive Motor Deficits

Rett syndrome (RTT) is a genetic disorder characterized by a range of features including cognitive impairment, gait abnormalities and a reduction in purposeful hand skills. Mice harbouring knockout mutations in the Mecp2 gene display many RTT-like characteristics and are central to efforts to find n...

Descripción completa

Detalles Bibliográficos
Autores principales: Gadalla, Kamal K. E., Ross, Paul D., Riddell, John S., Bailey, Mark E. S., Cobb, Stuart R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231076/
https://www.ncbi.nlm.nih.gov/pubmed/25392929
http://dx.doi.org/10.1371/journal.pone.0112889

Ejemplares similares

Ejemplares similares