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Hidden Disease Susceptibility and Sexual Dimorphism in the Heterozygous Knockout of Cyp51 from Cholesterol Synthesis

We examined the genotype-phenotype interactions of Cyp51(+/−) mice carrying one functional allele of lanosterol 14α-demethylase from cholesterol biosynthesis. No distinct developmental or morphological abnormalities were observed by routine visual inspection of Cyp51(+/−) and Cyp51(+/+) mice and fer...

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Detalles Bibliográficos
Autores principales:	Lewinska, Monika, Juvan, Peter, Perse, Martina, Jeruc, Jera, Kos, Spela, Lorbek, Gregor, Urlep, Ziga, Keber, Rok, Horvat, Simon, Rozman, Damjana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231084/ https://www.ncbi.nlm.nih.gov/pubmed/25393872 http://dx.doi.org/10.1371/journal.pone.0112787

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