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Aminoterminal Amphipathic α-Helix AH1 of Hepatitis C Virus Nonstructural Protein 4B Possesses a Dual Role in RNA Replication and Virus Production

Nonstructural protein 4B (NS4B) is a key organizer of hepatitis C virus (HCV) replication complex formation. In concert with other nonstructural proteins, it induces a specific membrane rearrangement, designated as membranous web, which serves as a scaffold for the HCV replicase. The N-terminal part...

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Detalles Bibliográficos
Autores principales:	Gouttenoire, Jérôme, Montserret, Roland, Paul, David, Castillo, Rosa, Meister, Simon, Bartenschlager, Ralf, Penin, François, Moradpour, Darius
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231108/ https://www.ncbi.nlm.nih.gov/pubmed/25392992 http://dx.doi.org/10.1371/journal.ppat.1004501

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